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| Disease found: | Sheehan Syndrome |
| Current as of: | October 8, 2024 |
| Disease Overview: | postpartum hypopituitarism; hypotension following postpartum hemorrhage causing ischemic pituitary necrosis [more info] |
| Signs and Symptoms: | Symptoms related to low pituitary hormones: failure to lactate (common), failure to resume regular menses, excessive fatigue, adrenal crisis. Symptoms may appear acutely or months-years after delivery. [more info] |
| Diagnosis: | Standard blood tests for pituitary hormone levels. Head CT/MRI will likely show empty sella; also rules out tumor. [more info] |
| Treatment: | Pituitary hormone replacement therapy as needed based on patient-specific deficiencies. [more info] |
| Clinical Management: | Long-term endocrinology support. Patients who desire additional children may need fertility assistance. Support group: Maternal Pituitary Support |
| Referral: | Managed by Endocrinology. Referral to Medical Genetics Department, if available. Initial virtual care is also available through organizations like TeleRare Health. |
| Clinical Trials: | Currently there are no active clinical trials. |